منابع مشابه
Hypoglycemia: Culprit or Bystander?
Corresponding author: You-Cheol Hwang http://orcid.org/0000-0003-4033-7874 Division of Endocrinology and Metabolism, Department of Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, 892 Dongnam-ro, Gangdong-gu, Seoul 05278, Korea E-mail: [email protected] In 2012, the American Diabetes Association (ADA) and the European Association for the Study of ...
متن کاملBystander or no bystander for gene directed enzyme prodrug therapy.
Gene directed enzyme prodrug therapy (GDEPT) of cancer aims to improve the selectivity of chemotherapy by gene transfer, thus enabling target cells to convert nontoxic prodrugs to cytotoxic drugs. A zone of cell kill around gene-modified cells due to transfer of toxic metabolites, known as the bystander effect, leads to tumour regression. Here we discuss the implications of either striving for ...
متن کاملUsing participant or non-participant observation to explain information behaviour
The aim of the paper is to provide guidance on conducting participant and non-participant observation studies of information behaviour. Examines lessons learned during nonparticipant observation of hospital pharmacists, and participant observation with dependent older people living in their own homes. Describes the methods used in both studies, and discusses the ethical issues involved in gaini...
متن کاملAlbumin: innocent bystander or culprit?
ALPORT SYNDROME (AS) is a hereditary glomerulopathy associated with hearing loss and ocular abnormalities that, if left untreated, inevitably progresses to glomerulosclerosis and endstage renal disease (ESRD) (6). AS is caused by mutations in collagen type IV genes and is associated with thickening and splitting of the glomerular basement membrane (GBM), ultimately rendering it leaky for albumi...
متن کاملInnocent Bystander or the Heel of Achilles.
Case Presentation A 29-year-old male presented with palpitations without a documented tachycardia. ECG showed minimal preexcitation (Figure 1A), and echo confirmed a normal heart. At electrophysiological study in the drug-free state, the HV interval was 13 ms in sinus rhythm, and ventricular (V) activation in the right paraHisian region preceded the surface delta wave (Figure 2A). Programmed st...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature
سال: 1976
ISSN: 0028-0836,1476-4687
DOI: 10.1038/259443b0